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glycanova seeks novel foods approval for lentinex
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danish company glycanova is waiting for a final opinion from the uk food standards agency (fsa) on its proposed lentinan-rich extract from shiitake mushrooms ( lentinus edodes ). lentinan is a form of beta-glucan produced by fermenting the mushrooms in glucose, malt extract, soy peptone and yeast extract, a process similar to the production of a number of food products, including baker’s yeast. the company wants to market its proposed lentinex product as a novel food supplement and novel food ingredient in a number of different food categories, including dietary supplements, yoghurts, soft drinks, cooked and processed foods, and baked goods. substantial equivalence the fsa states that a novel food is “a food or food ingredient that does not have a significant history of consumption within the european union before 15 may 1997 ” . according to eu legislation, before any new food product can be released on to the european market it must undergo a series of rigorous safety tests by the advisory committee on novel foods and processes (acnfp), an independent committee of scientists appointed by the fsa. glycanova had previously submitted an application in september 2006 under the “simplified procedure”, whereby a company applies to have its novel food recognized as “substantially equivalent” to an item already on the market. the company argued that shiitake mushrooms themselves have an established history of consumption throughout the eu and the rest of the world, and that lentinan is also found in legumes, cereals, tubers and fruits. moreover, it claimed that beta-glucans extracted from mushrooms, including shiitake mushrooms, are also consumed in concentrated form in a range of commercially available dietary supplements. however, the acnfp “concluded that the data provided by the applicant were insufficient to enable an opinion on substantial equivalence to be issued” . the company therefore had to submit a full application to have the product approved as a novel food. the acnfp has now formulated a draft opinion on which it is currently inviting comments before it finalises its decision. perceived health benefits tests have suggested that lentinan may be effective in the treatment of cancer, as well as having cholesterol-lowering and immune-regulatory properties. however, the draft opinion states that “any health claims that are attributed to the consumption of lentinan are not considered as part of this application” . were glycanova to make any health claims for lentinex, these would have to be examined separately under regulation (ec) 1924/2006. the company is proposing that its product be marketed without restriction with a recommended daily intake of 1-2.5mg/day. the application does not include any dietary survey data showing that these levels would not be exceeded but notes that daily consumption of four or five shiitake mushrooms would provide an intake of around 1.8mg. toxicology studies carried out on animals and humans by glycanova have not indicated that consumption of the product would give cause for concern. however, the acnfp has suggested that the primary purpose of the preliminary tests was to establish the efficacy of the product and that further toxicology reports would be required. lentinus edodes is native to asian countries with warm climates such as japan and china and is usually found growing on fallen deciduous trees. fresh shiitake mushrooms are widely available at supermarkets and health food stores across europe.
Source :Food Safety, HACCP, Food Quality, Food Microbiology, Hygiene
Date :
7
October
2008
Category :
restaurants and Food industrie
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japanese researchers in conjunction with the yale school of medicine have found the mushroom extract, ahcc, can strengthen the immune system and fight the onset of cancer among over-50s. ahcc (active hexose correlated compound) is an oligosaccharide that is extracted from several mushroom species and has been recommended to the elderly by japanese health professionals since 1987, according to maypro, a new york-based supplier of ahcc.
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one year on and the quality of soy sauce used in catering outlets in the uk appears to have improved. the uk food standards agency (fsa) recently carried out a survey and found fewer samples containing unacceptable levels of the chemical 3-mcpd compared with a retail survey published by the fsa last year. only 2 per cent of samples surveyed - 6 out of 273 - contained levels of 3-mcpd above the recently introduced european legal limit.
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the use of bisphenol a (bpa) in can linings is both safe and vital for food protection, a host of industry bodies and companies have said in rejecting the conclusions of a report calling for a ban on the chemical. the north american metal packaging alliance (nampa), the american chemistry council (acc), as well as food giants such as del monte, campbell and general mills have dismissed a study by the us-based consumer union that claimed potentially hazardous levels of bpa were leaching into foods from the epoxy linings of cans.
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a uk campaign group has called for stricter regulations on the formulation and labelling of supermarket bakery bread, after consumer group which? found that some fresh loaves contain twice as much salt as others. the campaign could affect the bakers which supply bakeries with fresh bread, as they may find themselves coming under tighter regulations in regards to how they bake and package the product.
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the controversial herbal ingredient kava, kava is once again in the news when the uk food standards agency this week announced that it is seeking views on draft regulations that would result in the removal from sale of food products containing or consisting of kava kava. kava kava is a herb commonly found in remedies but also in some food products. evidence has emerged recently that products containing kava kava may have a toxic effect on the liver.
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the uk joint health claims initiative (jhci) this week adopted and published advice from leading scientists promoting the role of fruit and vegetables in helping to avoid stomach, lung and bowel cancer and contributing to a healthy lifestyle. the advice comes after four months of study by seven leading scientists from the jhci expert committee. the researchers investigated available evidence on the possible relationship between fruit and vegetables and health.
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Coca.Cola
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PEPSI
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Mcdonald
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Nestle
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Mars
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Baskin & Robins
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Nutrika
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Mumika
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Chika
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the 
high dosages of 
a 