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scientists determine safe acrylamide levels
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tolerable intakes of acrylamide should be set at 2.6 micrograms per kilogram of body weight to avoid the cancer risk, says a new toxicology study from the us. this would be equivalent to 182 micrograms for a 70 kg human as a tolerable daily intake (tdi) for carcinogenic levels. the tdi for neurotoxicity was found to be higher, at 40 micrograms per kg per day, or 2,800 micrograms per day for a 70 kg human. both levels vastly exceed levels estimated by various national agencies or studies. health canada, for example, estimates the average exposure of adults to acrylamide in food to be between 0.3 and 0.4 micrograms per kilogram of body weight per day, while a study from sweden estimated intakes of about 0.5 micrograms per kilogram of bodyweight. the us food and drug administration (fda) estimated intakes to be around 0.4 micrograms per kilogram of bodyweight per day. the study, funded by the grocery manufacturers association (gma), used a state-of-the-art physiologically-based toxicokinetic model to compare doses of acrylamide and its metabolite glycidamide in humans and rats. the researchers, led by robert tardiff from the sapphire group inc. in bethesda, maryland, report their findings in food and chemical toxicology. “overall, we conclude that the tdis and margins of exposure for average exposures to acrylamide in cooked foods provide an adequate margin of safety to preclude neurotoxicity as well as tumor formation,” wrote the researchers. “the certainty in our conclusions is relatively high because of reliance on relying on findings from our updated human internal dosimetry model and a reasonable understanding of acrylamide’s modes of action,” they added. clicktag = false; sas.call( 'textad' ); sas.overlays[ 'textad' ] = clicktag; acrylamide story acrylamide is a suspected carcinogen that is formed during by heat-induced reaction between sugar and an amino acid called asparagine. known as the maillard reaction, this process is responsible for the brown colour and tasty flavour of baked, fried and toasted foods. despite being a carcinogen in the laboratory, many epidemiological studies have reported that everyday exposure to acrylamide in food is too low to be of concern. the compound first hit the headlines in 2002, when scientists at the swedish food administration first reported unexpectedly high levels of acrylamide, found to cause cancer in laboratory rats, in carbohydrate-rich foods. since the swedish discovery a global effort has been underway to amass data about this chemical. more than 200 research projects have been initiated around the world and their findings co-ordinated by national governments, the eu and the united nations. source: food and chemical toxicology published online ahead of print, doi: 10.1016/j.fct.2009.11.048 "estimation of safe dietary intake levels of acrylamide for humans" authors: r.g. tardiff, m.l. gargas, c.r. kirman, m.l. carson, l.m. sweeney.
Source :foodnavigator.com
Date :
8
December
2009
Category :
Food And Health
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vitamin b3 may inhibit the formation of acrylamide in french fries by over 50 per cent, according to a new study from china. in a model system, both vitamins b3 and b6 in the pyridoxine form were able to inhibit over 70 per cent of the formation of the carcinogen, suggest findings published in the journal food chemistry . “the effectiveness of vitamin b3 was eventually corroborated in fried potato strips, thus suggesting its great potential for application in food processing to decrease acrylamide formation,” wrote the authors, led by xiaohui zeng from the university of hong kong.
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using amino acids to compete with, and reduce, the sources of acrylamide should focus on the common additive cysteine, according to results from belgium. according to a study published in the journal food chemistry , l-cysteine may reduce the concentration of acrylamide by more than 99 per cent. “selectively increasing the free amino acid pool to compete with asparagine for available carbonyls and/or to enhance the elimination of acrylamide has already been proposed as a possible mitigation mechanism for acrylamide generation,” explained lead author kristel de vleeschouwer from the leuven food science and nutrition research centre (lforce) at the catholic university of leuven.
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too much snacking on potato chips may increase the risk of hardening of the arteries, and raise the risk of cardiovascular disease, says a joint polish-swedish study. according to findings published in the new issue of the american journal of clinical nutrition , consuming 160 grams of potato chips per day may increase levels of compounds linked to oxidative stress and inflammation, both of which may increase the risk of certain chronic disease.
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a snapshot survey of process chemicals in food products sold in the uk has found that potato snacks contained the highest levels of acrylamide, but the impact of initiatives like the ciaa acrylamide toolbox will only really be seen in future surveys. acrylamide is a suspected carcinogen that is formed during by heat-induced reaction between sugar and an amino acid called asparagine.
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the ciaa has included asparaginase in the new version of its acrylamide toolbox, a move seen to validation the efforts of companies that have developed commercial solutions using the acrylamide-reducing enzyme. acrylamide is a suspected carcinogen that is formed during by heat-induced reaction between sugar and an amino acid called asparagine. known as the maillard reaction, this process is responsible for the brown colour and tasty flavour of baked, fried and toasted foods.
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Coca.Cola
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PEPSI
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Mcdonald
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Nestle
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Mars
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Chika
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